Replace Elements Of A Non-array String Using Datasplits?

Let's say I have regular string called tempstring, and I want to change a specific item in that string. Like if tempstring = ";1;2;3" and I want to change the "2" to "Baboon." Here's my best solution on how to do it:

vb
Tempstring = ";1;2;3"
'Datasplit tempstring
Dim datasplit As String() = Tempstring.Split(New Char() {";"c})

[Code]....

This works, however, it feels a little heavy. Is there an easier way to do this? Perhaps a way to directly replace datasplits without readding them all to another string one by one using a loop?