Game Programming - Detect The Collision Of NPC's That Load Onto 2d Tile Map From Text File

I have a question about collision, yes my 2d tile rpg's map collision works just fine, but im having trouble with the collision with my npc's. At the start of the game it loads all the map data from a text file. well it also loads the location and other stuff about the npc's onto the map from a text file. how do i detect the collision of the npc's that were loaded from the text file, i could do collision with hardcoded npc's but i want to avoid hardcoding the game content into the game engine. RESTATING MY QUESTION: How do i detect the collision of NPC's that i load onto my 2d tile map from text file?