Read/write Some Data ?

My first question has to do with the opening lines needed in a VB program in order to connect to Excel 2007 and read/write some data from/to it. I know the process only slightly and reading and writing to the cells is not my real concern for the moment. What I need to become familliar with are the lines like this:

CODE:

This is just one of the examples I have read through and to be honest I only follow this slightly. The trouble was that with each new article I read, people did this differently, not the variables on the left mind you, just that some left out lines, which I can see could be done based on circumstances. Still others said the Imports line was not needed....etc...and other loaded up at least 3 or four more Imports lines insisting all were needed.

I'm looking for some straight-forward advice on what is the minimum needed to access an existing Excel spreadhseet and to just read some of it's cells to variables in the code and then writed some data back to certain cells within the spreadsheet and then save and close it.

Also, please note that I am using VB 2010 Express. Why, because I'm a broke developer who spent most of last year out of work. I have a new contract assignment which is so far going well but will go even better if I can master this technique with VB.NET, not VBA. And all the docs I've read said that even though VB 2010 Express is a watered down version of VS, I should be able to do medium level tasks such as this with it.