Read A File As A Set Of Numbers Such As Long Integers?

Is there a correct way of doing this in vb.net? I want to read a file as a set of numbers such as long integers ,say the file contains the string "Hello World - Its a beautiful day blah blah blah" This would read as a set of long integers that are 4 bytes long

ie ascii (hex)
48 65 6C 6C 6F 20 57 6F
H e l l o W o

etc and that would also be an 4 byte word represented as a number 1819043144 thus stepping through the file 4 bytes at a time. Instead of reading and looking for certain words in the file I would look for certain numbers, thus eliminating read errors in certain file types. I coded this type of thing in vb6 before , this would be done with the 'get' method and a file pointer. I have managed to read it a byte at a time with this code but I am unsure where to go with it as the 'get' method isn't in vb.net

Imports System.IO
Imports System.Text
Public Class Form1

[Code].......